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RFDiffusionContigmapConfig

Provides interface for passing contigmap configuration to RF Diffusion node.

RFDiffusionContigmapConfig

Quick Start

  1. Add the RFDiffusionContigmapConfig node to your workflow.
  2. Specify masking and unmasking regions as needed for your design.
  3. Connect the output to the RF Diffusion node's contigmap_config input.

Setup Guide

1. Add Node to Workflow

  1. Insert the RFDiffusionContigmapConfig node from the node palette.
  2. Connect it to the contigmap_config input of the RF Diffusion node.

2. Configure Parameters

  1. Set masking and unmasking regions using the input fields:
    • Use the same format as for contigs (e.g., A10-25, 5-15).
    • Leave fields empty if not required.

Basic Usage

Masking Sequence Regions

  • Use inpaint_seq to mask specific amino acid sequence regions.
  • Use inpaint_str to mask 3D structure indices.
  • Use provide_seq to unmask specific sequence regions.
  • Use length to define the length or range for the region.

Configuration

Required Inputs

Field Description Type Example
inpaint_seq Amino acids whose sequence should be masked (contigs format). STRING A10-25
inpaint_str Indices for masking the 3D structure. STRING B165-178
provide_seq Inclusive ranges of sequence regions to unmask. STRING 172-177,200-205
length Length or range of sequence length. STRING 100 or 100-150

Optional Inputs

None

Outputs

Field Description Example
contigmap_config Configuration dict for RF Diffusion node. {"inpaint_seq": ["A10-25"], ...}

Best Practices

Parameter Formatting

  • Use the same format as for RF Diffusion contigs (e.g., A10-25, 5-15).
  • Leave fields empty if not needed for your use case.

Workflow Integration

  • Always connect this node to the contigmap_config input of the RF Diffusion node for advanced masking/unmasking.

Troubleshooting

Common Issues

  • Incorrect format in input fields: Ensure you use the correct contigs format (e.g., A10-25).
  • Unexpected results in RF Diffusion: Double-check that masking/unmasking regions are specified as intended.

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